Synthesis of indigogenic substrates. Investigation of Salmonella esterase activity

Article abstract of DOI:10.1016/0223-5234(90)90135-P

The synthesis of chromogenic compounds of indoxyl as substrates is described. A first series is obtained from unsubstituted indoxyl esters and C7-C10 fatty acids. The 5 or 6-monosubstituted bromine or chlorine derivatives of indigogenic esters and 4,5 or 5, 6-disubstituted derivatives are synthezised in the second step. Some of them are evaluated on esterase activity in Salmonella cultures. The 5-bromo-indoxyl pelargonate derivative exhibits the most interesting results.