European Journal of Medicinal Chemistry p. 697 - 699 (1990)
Update date:2022-08-03
Topics:
Agban
Ounanian
Luu-Duc
Monget
The synthesis of chromogenic compounds of indoxyl as substrates is described. A first series is obtained from unsubstituted indoxyl esters and C7-C10 fatty acids. The 5 or 6-monosubstituted bromine or chlorine derivatives of indigogenic esters and 4,5 or 5, 6-disubstituted derivatives are synthezised in the second step. Some of them are evaluated on esterase activity in Salmonella cultures. The 5-bromo-indoxyl pelargonate derivative exhibits the most interesting results.
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