GABA uptake inhibitors. Syntheses and structure-activity studies on GABA analogues containing diarylbutenyl and diarylmethoxyalkyl N-substituents

DOI: 10.1016/0223-5234(91)90214-8

Source and publish data:

European Journal of Medicinal Chemistry p. 69 - 77 (1991)

Update date:2022-08-03

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Authors:

Falch Falch

Krogsgaard-Larsen

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Article abstract of DOI:10.1016/0223-5234(91)90214-8

A number of analogues of GABA or β-alanine containing 4,4-diphenyl-3-butenyl (DPB), benzhydryl ethyl ether (BEE), or benzhydryl propyl ether N-substituents have been synthesized and tested as inhibitors of synaptosomal GABA uptake. Whereas the N-DPB and N

Full text of DOI:10.1016/0223-5234(91)90214-8

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