Synthesis and antibacterial activity of some imidazo[1,2-a[pyrimidine derivatives

DOI: 10.1248/cpb.40.1170

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1170 - 1176 (1992)

Update date:2022-08-05

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Authors:

Rival Rival

Grassy Grassy

Michel Michel

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Article abstract of DOI:10.1248/cpb.40.1170

A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The 'in vitro' antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.

Full text of DOI:10.1248/cpb.40.1170

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