Synthesis and antibacterial activity of some imidazo[1,2-a[pyrimidine derivatives

DOI: 10.1248/cpb.40.1170

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1170 - 1176 (1992)

Update date:2022-08-05

Topics:

Authors:

Rival Rival

Grassy Grassy

Michel Michel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.1170

A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The 'in vitro' antibacterial activity of these compounds and their corresponding α-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.

Full text of DOI:10.1248/cpb.40.1170

NII-Electronic Library Service

Products guided by the article

Product name:1-(4-Imidazo[1,2-a]pyrimidin-2-yl-phenyl)-ethanone

Cas No:134044-49-8

R&D Labs maybe for 134044-49-8

Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
SHIJIAZHUANG CHENSHI IMPORT AND EXPORT CO.,LTD

Contact:+86-311-89871056

Address:RM2017 BUILDING CTIANSHAN GALAXY PLAZA,NO168 CHANGJIANG ROAD,GAOXIN DISTRICT,SHIJIAZHUANG CITY, HEBEI,CHINA
Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China

Relevant to this article

Enantioselective synthesis of glutarimide alkaloids cordiarimides A, B, crotonimides A, B, and julocrotine

Doi:10.1002/cjoc.201180248
(2011)
Synthesis of congeners of migrastatin and dorrigocin A from d-xylose

Doi:10.1016/j.tetlet.2010.07.141
(2010)
Lewis Acid Catalyzed Ene Reactions of α,β-Unsaturated N-Acyloxazolidinones

Doi:10.1021/jo00016a019
(1991)
The Synthesis of Heterobifunctional Linkers for the Conjugation of Ligands to Molecular Probes

Doi:10.1021/jo00013a053
(1991)
Synthesis of dihydro-1,2,4-triazolo[1,5-a]pyrimidines

Doi:10.1055/s-1991-26414
(1991)
A new pyrazolone based ternary Cu(II) complex: Synthesis, characterization, crystal structure, DNA binding, protein binding and anti-cancer activity towards A549 human lung carcinoma cells with a minimum cytotoxicity to non-cancerous cells

Doi:10.1016/j.poly.2013.08.051
(2013)

Article Doi