Palladium (O) catalyzed tandem alkylation and SN′ cyclization of 1,4-dichlorobut-2-ene by the N-(diphenylmethylene)acetonitrile. a stereoselective synthesis of 1-aminocyclopropanecarboxylic acids

Article abstract of DOI:10.1016/0040-4039(95)00381-L

Racemic coronamic acid has been prepared with 100% diastereoselectivity from one pot palladium (O) catalyzed alkylation and S_N′ cyclization of 1,4-dichlorobut-2-ene by the benzophenone Schiff base of aminoacetonitrile.