A NEW ALKYLATION METHOD OF THE CARBON α TO THE NITROGEN OF SECONDARY AMINES

Article abstract of DOI:10.1016/0040-4039(91)80353-8

A route to the alkylation of the carbon α to the nitrogen of secondary amines 1a,c-g is proposed which is based upon a new and efficient synthesis of oxazolidines 3 from β-hydroxy tertiary amine N-oxides 2.