Journal of Organic Chemistry p. 4435 - 4439 (1991)
Update date:2022-08-03
Topics:
Kim, Yong-Joo
Bernstein, Max P.
Galiano Roth, Angela S.
Romesberg, Floyd E.
Williard, Paul G.
et al.
Enolizations of ketones, tert-butyl esters, and carboxamides by solvent-free lithium diisopropylamide (LDA) in hexane or toluene are described.Enolates are isolated as spectroscopically pure, white (often crystalline) solids.Solubilities of the enolates in hexane range from highly soluble to completely insoluble.Enolization of aldehydes, methyl esters, and acetone afford complex mixtures.Analysis of <6Li>LDA and <6Li,15N>LDA in hexane by 6Li and 15N NMR spectroscopy show evidence of an equilibrium mixture of at least three cyclic oligomers.
View MoreYangzhou Zhongbao Pharmaceutical Co.,Ltd
Contact:+86-514-88290838
Address:Jiangsu Baoying county economic develpment zone in baoying avenue91
HANGZHOU GOPHER CHEM-TECH CO.,LTD
Contact:86-189-58111780
Address:Da Cheng Ming Zuo Plaza,Xiaoshan District
KangZhiYuan Pharmaceutical Company Limited
Contact:(Sabrina)86-20-85273232
Address:4th floor, building B, Dadi industry zone, Tangxia, Tianhe, Guangzhou, China
lianyungang jinkang pharmaceutical technology co., ltd.
Contact:008651885445517
Address:Jinshan industrial park, Ganyu county, Lianyungang, Jiangsu Province, 222115, China
Taizhou Elitechemie MediPharma Technology Co.,Ltd.
Contact:+86-523-86810021
Address:Building G14,NO.1 Avenue,China Medical City, Taizhou, Jiangsu,China
Doi:10.1039/jr9590002153
(1959)Doi:10.1021/jo01039a029
(1963)Doi:10.1039/c39860001046
(1986)Doi:10.1007/BF02766101
(1891)Doi:10.1007/BF00542790
(1986)Doi:10.1248/cpb.34.4075
(1986)
