Synthesis and anti-neuroinflammatory activity studies of substituted 3,4-dihydroquinoxalin-2-amine derivatives

Article abstract of DOI:10.1016/j.tetlet.2012.03.057

We demonstrate the synthesis of multifunctional 3,4-dihydroquinoxalin-2- amine derivatives 4 through a three-component condensation reactions of a substituted o-phenylenediamines 1 (OPDA), diverse ketones 2 and various isocyanides 3 in the presence of a c