Journal of the Chemical Society. Chemical communications p. 571 - 572 (1991)
Update date:2022-09-26
Topics:
Zabriskie, T. Mark
Cheng, Hengmiao
Vederas, John C.
Incubation of D-phenylalanyl-L-phenylalanylglycine with peptidylglycine α-amidating monooxygenase (PAM) in the presences of 18O2 generates the corresponding hydroxyglycyl peptide whose FAB mass spectrum shows high incorporation of 18O into the hydroxy group; this suggests that the mechanism may involve direct hydroxylation of carbon.
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