Copper(i)-catalyzed synthesis of 1,3-enynes via coupling between vinyl halides and alkynes or domino coupling of vinyl halides

DOI: 10.1039/c1ob06210g

Source and publish data:

Organic and Biomolecular Chemistry p. 7309 - 7312 (2011)

Update date:2022-08-05

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Authors:

Zhu, Yan

Li, Tingyi

Qu, Xiaoming

Sun, Peng

Yang, Hailong

Mao, Jincheng

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Article abstract of DOI:10.1039/c1ob06210g

1,3-Enynes were easily prepared from coupling between vinyl halides and alkynes or domino coupling of vinyl halides in the presence of copper iodide. It is noteworthy that the double-bond geometry of the vinyl halides was retained during the reaction. This ligand-free protocol is potentially useful and practical.

Full text of DOI:10.1039/c1ob06210g

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