Complex Induced Proximity Effects: β-Lithiations of Carboxamides

DOI: 10.1021/jo00016a025

Source and publish data:

Journal of Organic Chemistry p. 4938 - 4943 (1991)

Update date:2022-08-03

Topics:

Authors:

Lutz, Gary P.

Wallin, Anne P.

Kerrick, Shawn T.

Beak, Peter

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Article abstract of DOI:10.1021/jo00016a025

The R*,S* and R*,R* diastereomers of N,N-diisopropyl-2,3-dideuterio-2-methyl-3-phenylpropanamide (5,6) have been used to investigate the diastereoselectivity of the β-lithiation of N,N-diisopropyl-2-methyl-3-phenylpropanamide (4).The β-lithiation of 4 is

Full text of DOI:10.1021/jo00016a025

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