Tetrahedron p. 10431 - 10442 (1994)
Update date:2022-08-04
Topics: Synthesis Regioselectivity Yield Catalyst Solvent Enantioselectivity Nucleoside Mass spectrometry (MS) Nucleophilic substitution Cyclopropanation Deprotection HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Protecting group Purification Glycosylation Coupling Reaction Reaction Optimization Carbocyclic Cyclopropyl
Csuk, Rene
Scholz, Yvonne von
As representatives of a novel class of carboxylic nucleoside analogues (+/-)-cis-, (-)-cis and (+/-)-trans 9-(2-hydroxymethylcyclopropyl)-adenine (= <2-(6-amino-purin-9-yl)-cyclopropyl>-methanol) were synthesized from the corresponding dialkyl 1,2-cyclopropane dicarboxylates.
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Doi:10.1590/S0103-50532011001000015
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(2017)Doi:10.1016/S0040-4039(00)74355-3
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