A novel access to 4-fluoropyrimidines from α-chloro-α'-trifluoromethylketones

Article abstract of DOI:10.1016/S0040-4039(00)74355-3

When treated with formamidine acetate and KOH, α-chloro-α'-trifluoromethyl ketones afford, though in moderate yield, 4-fluoropyrimidine derivatives.