SYNTHESIS OF 5'-O-PHOSPHONOMETHYL-2',3'-DIDEHYDRO-2',3'-DIDEOXYURIDINE BY USE OF P-METHOXYBENZYL AS A N3-PROTECTING GROUP.

DOI: 10.1016/S0040-4039(00)85994-8

Source and publish data:

Tetrahedron Letters p. 1905 - 1908 (1991)

Update date:2022-08-05

Topics:

Authors:

Aerschot, A. Van

Jie, L. Jie, L.

Herdewijn, P.

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Article abstract of DOI:10.1016/S0040-4039(00)85994-8

Uridine derivatives are protected at N³-position with a p-methoxybenzyl group under Mitsunobu conditions.Selective removal is possible with ceric ammonium nitrate.The otherwise difficult to obtain 5'-O-phosphonomethyl d4U was prepared using thi

Full text of DOI:10.1016/S0040-4039(00)85994-8

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