Unexpected formation of 6,7-dihydrobenzo[4′,5′]imidazo- [1′,2′:1,6]pyrimido[5,4-a]indolizine derivative in the alkylation of 2-amino-1-(benzimidazol-2-yl)-3-(4-methoxybenzoyl)indolizine

Article abstract of DOI:10.1134/S1070363211100227

An attempt to effect exhaustive alkylation of 2-amino-1-(benzimidazol-2-yl) -3-(4-methoxybenzoyl) indolizine with alkyl iodides in boiling acetone led to the formation of 6,6-dimethyl-8-(4-methoxybenzoyl)-6,7-dihydrobenzo[4′, 5′]imidazo[1′,2′:1,6]pyrimido[5,4-a]indolizine instead of expected N-alkyl derivatives. The product structure was proved by X-ray analysis. Pleiades Publishing, Ltd., 2011.