5′-O-(4-4′-dimethylthoxytrityl)-4-thiocyanatothymidine A useful intermediate for the preparation of various 4-substituted thymidine analogues

Article abstract of DOI:10.1016/S0040-4039(00)74367-X

The thiocyanato group in 5′-O-(4,-4′-dimethoxytrityl)-4-thiocyanatothymidine 2 is easily displaced by a variety if O-, N=- and S-nucleophiles, making this compound a useful intermediate for the preparation of 4-substituted thymidine analogues.