Tetrahedron Letters p. 1715 - 1718 (1991)
Update date:2022-08-02
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Pon, Richard T.
An N-dimethoxytritylated biotin group coupled to a 6-aminohexanol linker was converted into a phosphoramidite to yield a biotinylating reagent which can be used in automated solid-phase synthesis to produce 5'-biotinylated oligonucleotides in high yields.
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