Journal of Fluorine Chemistry p. 149 - 157 (1991)
Update date:2022-08-04
Topics: Synthesis Melting point NMR spectroscopy Catalyst Nucleophile Electrophile Solvent Chromatography Recrystallization Mass spectrometry (MS) Purification Reaction Mechanism Substitution Reaction Reaction Optimization Heterocyclic compound Reaction yield Oxazole Carboxylic acid (-COOH)
Shi, Guoqiang
Xu, Yuanyao
Xu, Ming
5-Ethoxy-4-(trifluoromethyl)-2-oxazolecarboxylic acid 4 has been obtained from the corresponding ethyl ester prepared by rhodium-catalysed reaction of ethyl 3,3,3-trifluoro-2-diazopropionate 1 with ethyl cyanoformate.Starting from this acid, a number of i
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Doi:10.1055/s-0035-1561630
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