A CONVENIENT SYNTHESIS OF 5-ETHOXY-4-(TRIFLUOROMETHYL)-2-OXAZOLECARBOXYLIC ACID AND RELATED TRIFLUOROMETHYL SUBSTITUTED HETEROCYCLIC COMPOUNDS

DOI: 10.1016/S0022-1139(00)80131-1

Source and publish data:

Journal of Fluorine Chemistry p. 149 - 157 (1991)

Update date:2022-08-04

Topics: Synthesis Melting point NMR spectroscopy Catalyst Nucleophile Electrophile Solvent Chromatography Recrystallization Mass spectrometry (MS) Purification Reaction Mechanism Substitution Reaction Reaction Optimization Heterocyclic compound Reaction yield Oxazole Carboxylic acid (-COOH)

Authors:

Shi, Guoqiang

Xu, Yuanyao

Xu, Ming

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0022-1139(00)80131-1

5-Ethoxy-4-(trifluoromethyl)-2-oxazolecarboxylic acid 4 has been obtained from the corresponding ethyl ester prepared by rhodium-catalysed reaction of ethyl 3,3,3-trifluoro-2-diazopropionate 1 with ethyl cyanoformate.Starting from this acid, a number of i

Full text of DOI:10.1016/S0022-1139(00)80131-1

Products guided by the article

Product name:5-Ethoxy-4-trifluoromethyl-oxazole-2-carboxylic acid phenyl ester

Cas No:135244-93-8

R&D Labs maybe for 135244-93-8

Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Taimai Sanluck Pharmaceutical Co.,Ltd

Contact:86-592-7662921

Address:8D,No.186,Huarong Road,Huli,Xiamen,China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
Synasia Inc

Contact:17316303296

Address:240 Amboy Ave
Xi'an Costrong Pharmaceutical Co., Ltd.

Contact:029- 68576496

Address:Room 2004,Shuibao Building,No.190,South Erhuan Rd, Yanta District,Xi'an,Shaan Xi,China

Relevant to this article

Nickel(II)-Catalyzed Asymmetric Michael Addition of Oxindoles with Modified N,N,O-Tridentate Chiral Phenanthroline Ligands

Doi:10.1055/s-0035-1561630
(2016)
Synthetic approaches to 9-arylated Cinchona alkaloids: Stereoselective addition of Grignard reagents to cinchonanones and hydroxylation of 9-phenylcinchonanes

Doi:10.1016/j.tetasy.2012.05.024
(2012)
Symmetric and dissymmetric N-heterocyclic carbene rhodium(I) complexes: A comparative study of their catalytic activities in transfer hydrogenation reaction

Doi:10.1002/aoc.2857
(2012)
Synthesis, Spectroscopic Studies of Fluorinated Pyrimido-1,2,4-Triazines: Protective Effect Against Some Plant Pathogenic Fungi

Doi:10.1002/jhet.2386
(2016)
A new synthetic strategy for catechin-class polyphenols: Concise synthesis of (-)-epicatechin and its 3-O-gallate

Doi:10.1039/c2cc33704e
(2012)
Electronic helix theory-guided rational design of kinetic resolutions by means of the Sharpless asymmetric dihydroxylation reactions

Doi:10.1016/j.tet.2012.06.102
(2012)

Article Doi