A CONVENIENT SYNTHESIS OF 5-ETHOXY-4-(TRIFLUOROMETHYL)-2-OXAZOLECARBOXYLIC ACID AND RELATED TRIFLUOROMETHYL SUBSTITUTED HETEROCYCLIC COMPOUNDS

DOI: 10.1016/S0022-1139(00)80131-1

Source and publish data:

Journal of Fluorine Chemistry p. 149 - 157 (1991)

Update date:2022-08-04

Topics: Synthesis Melting point NMR spectroscopy Catalyst Nucleophile Electrophile Solvent Chromatography Recrystallization Mass spectrometry (MS) Purification Reaction Mechanism Substitution Reaction Reaction Optimization Heterocyclic compound Reaction yield Oxazole Carboxylic acid (-COOH)

Authors:

Shi, Guoqiang

Xu, Yuanyao

Xu, Ming

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0022-1139(00)80131-1

5-Ethoxy-4-(trifluoromethyl)-2-oxazolecarboxylic acid 4 has been obtained from the corresponding ethyl ester prepared by rhodium-catalysed reaction of ethyl 3,3,3-trifluoro-2-diazopropionate 1 with ethyl cyanoformate.Starting from this acid, a number of i

Full text of DOI:10.1016/S0022-1139(00)80131-1

Products guided by the article

Product name:5-Ethoxy-4-trifluoromethyl-oxazole-2-carboxylic acid phenyl ester

Cas No:135244-93-8

R&D Labs maybe for 135244-93-8

Zibo Kunran Enterprises Co. LTD

website:http://www.kunranchem.com

Contact:0086 533 5200669

Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
Water Chemical Co.,LTD

Contact:+86-21-6856-1349 523-87676172

Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
KINHENG CHEMICAL(SHANGHAI)CO., LTD.

Contact:+8621-60490170

Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.
ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Bejing Famous Pharmaceutical Technology Co., Ltd

website:http://www.peking-pharmacy.com

Contact:86-316-3097308

Address:Hangwang road, Yanjiao Economic and Technological Development Zone, Hebei, 65200,China

Relevant to this article

Nickel(II)-Catalyzed Asymmetric Michael Addition of Oxindoles with Modified N,N,O-Tridentate Chiral Phenanthroline Ligands

Doi:10.1055/s-0035-1561630
(2016)
Synthetic approaches to 9-arylated Cinchona alkaloids: Stereoselective addition of Grignard reagents to cinchonanones and hydroxylation of 9-phenylcinchonanes

Doi:10.1016/j.tetasy.2012.05.024
(2012)
Symmetric and dissymmetric N-heterocyclic carbene rhodium(I) complexes: A comparative study of their catalytic activities in transfer hydrogenation reaction

Doi:10.1002/aoc.2857
(2012)
Synthesis, Spectroscopic Studies of Fluorinated Pyrimido-1,2,4-Triazines: Protective Effect Against Some Plant Pathogenic Fungi

Doi:10.1002/jhet.2386
(2016)
A new synthetic strategy for catechin-class polyphenols: Concise synthesis of (-)-epicatechin and its 3-O-gallate

Doi:10.1039/c2cc33704e
(2012)
Electronic helix theory-guided rational design of kinetic resolutions by means of the Sharpless asymmetric dihydroxylation reactions

Doi:10.1016/j.tet.2012.06.102
(2012)

Article Doi