Tetrahedron Letters p. 2409 - 1412 (1991)
Update date:2022-08-04
Topics:
Nokami
Ohkura
Dan-Oh
Sakamoto
(+)-Brefeldin A (1) was synthesized by using (+)-4-cyanomethylcyclopent-2-en-1-one (2) as a key compound. 4-Hydroxy-2-enoate functionality was built by the reaction of the aldehyde (7) with (S)-ethyl p-chlorophenylsulfinylacetate.
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(2011)Doi:10.1021/om201041z
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(2011)
