European Journal of Medicinal Chemistry p. 221 - 230 (1991)
Update date:2022-08-03
Topics:
Nakib, T.A.
Bezjak, V.
Rashid, S.
Fullam, B.
Meegan, M.J.
This paper describes the synthesis of a series of 2-amino-4-aryl-4H,5H-<1>benzothiopyrano<4,3-b>pyran-3-carbonitriles and 2-alkoxy-4-aryl-5H-<1>benzothiopyrano<4,3-b>pyridine-3-carbonitriles.All of these products were studied for antifungal activity and many of these compounds displayed good activity against Cryptococcus neoformans, Torulopsis glabrata, and Trichosporon cutaneum.
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