
Journal of Medicinal Chemistry p. 2759 - 2767 (1991)
Update date:2022-07-29
Topics:
Vyplel, Hermann
Scholz, Dieter
Macher, Ingolf
Schindlmaier, Karl
Schuetze, Eberhard
The synthesis of a series of novel analogues of lipid A, the lipophilic terminal of lipopolysaccharides (LPS), and lipid X, the reducing monosaccharide unit in lipid A, is reported.In these compounds, the native 1-O-phosphate group has been replaced by a
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