Studies on cardiotonic agents. VII. Potent cardiotonic agent KF15232 with myofibrillar Ca2+ sensitizing effect

DOI: 10.1248/cpb.39.900

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 900 - 910 (1991)

Update date:2022-08-05

Topics: Experimental terms Cardiotonic agent

Authors:

Nomoto Nomoto

Takai Takai

Ohno Ohno

Kubo Kubo

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Article abstract of DOI:10.1248/cpb.39.900

A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3-(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inot

Full text of DOI:10.1248/cpb.39.900

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