A NEW SYNTHESIS OF OLIGODEOXYNUCLEOSIDE METHYLPHOSPHONATES ON CONTROL PORE GLASS POLYMER SUPPORT USING PHOSPHITE APPROACH

DOI: 10.1016/S0040-4039(00)81553-1

Source and publish data:

Tetrahedron Letters p. 877 - 880 (1983)

Update date:2022-08-05

Topics:

Authors:

Sinha, N. D.

Grossbruchhaus, V.

Koester, H.

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Article abstract of DOI:10.1016/S0040-4039(00)81553-1

Dimer, trimer and tetramer blocks of deoxynucleoside methylphosphonodiesters d(AC), d(AT), d(ATG) and d(ATTT) were synthesized on CPG polymer support using deoxynucleoside methylphosphonomonochloridite.Only dinucleotide methylphosphonates were phosphoryla

Full text of DOI:10.1016/S0040-4039(00)81553-1

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