Tetrahedron Letters p. 3191 - 3194 (1991)
Update date:2022-09-26
Topics:
Bueno, Ana B.
Carmen Carreno
Fischer, Jean
Garcia Ruano
Pena, Begona
Penas, Lorenzo
Rubio, Almudena
The reactions of (S2,Rs) and (R2,Rs)-2-p-tolylsulfinylcyclohexanones with AlMe3/ZnClz only yield the cyclohexylmethylcarbinols with R configuration at hydroxylic carbon. The (R1,S2,Rs)-1-methyl-2-p-tolysulfinylcyclopentanol was the only compound obtained in the reaction of Me3Al with both epimeric 2-p-lolysulfinyleyclopentanones. The d.e. of both reactions are higher than 96%.
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