
Helvetica Chimica Acta p. 892 - 898 (1991)
Update date:2022-08-02
Topics:
Charubala, Ramamurthy
Sobol, Robert W.
Kon, Ning
Suhadolnik, Robert J.
Pfleiderer, Wolfganag
The four protected diastereoisomers 7a/7b and 8a/8b of P-thioadenylyl-(3'-5')-P-thioadenylyl-(3'-5')-adenosine were synthesized, separated, and deblocked to the free oligonucleotides (Scheme).Biochemical characterization of these (3'-5')phosphorothioate a
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