Tetrahedron Letters p. 4905 - 4906 (1991)
Update date:2022-08-03
Topics: Synthesis Enantiomer Chiral Enantioselective Chemical Reaction Experimental Girolline
Commercon, A.
Paris, J. M.
Girolline (RP 49532) is efficiently and enantioselectively synthesized from the aldol reaction of (R)-3-chloroacetyl-4-isopropyl-1,3-oxazolidin-2-one 2 and 1-triphenylmethylimidazole-4-carboxaldehyde 3 followed by reaction with aqueous ammonia and reducti
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