Structure-activity relationship of 99mTc complexes of phenylenediamine- thiol-thioether ligands (PhAT) to brain uptake in rats

DOI: 10.1021/jm00053a010

Source and publish data:

Journal of Medicinal Chemistry p. 81 - 86 (1993)

Update date:2022-09-26

Topics:

Authors:

McBride McBride

Baldwin Baldwin

Kerr Kerr

Schultze

Salazar Salazar

Chinitz Chinitz

Byrne Byrne

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00053a010

A novel class of ligands, phenylenediamine-thiol-thioether (PhAT), was synthesized, and their ^99mTc complexes were evaluated for potential use as a functional brain imaging agent. The ligands reacted with Na^99mTcO₄ and SnC

Full text of DOI:10.1021/jm00053a010

Products guided by the article

Product name:4,5,1,8-Benzodithiadiazecine, 1,2,3,6,7,8-hexahydro-3,3,6,6-tetramethyl-

Cas No:135937-76-7

R&D Labs maybe for 135937-76-7

Cangzhou Senary Chemical Science-tech Co., Ltd

Contact:+86-317-3563899, 3563699

Address:168 Jinde Road, Cangzhou, Hebei, China
JIANGXI ZHANGFENG CHEMICAL CO., LTD.

Contact:+86-0799-3413066

Address:Xiyuan village, Xiabu Town, Xiangdong District
Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Chengdu Pukang Biotechnology Co., Ltd

website:http://www.pu-kang.com

Contact:86-028-63976226

Address:No. 868 Xiwang Road,Xinjin county,Chengdu city, China

Relevant to this article

Hydrophosphination of carbodiimides using protic heptaphosphide cages: A unique effect of the bimodal activity of protonated group 15 Zintl ions

Doi:10.1021/om300072z
(2012)
Synthesis, characterization, and pharmacological evaluation of 1-[2-(6-nitro-4-oxo-2-phenyl-4H-quinazolin-3-yl)-ethyl]-3-phenyl ureas

Doi:10.1007/s00044-012-0004-3
(2013)
Doi:10.1002/jps.2600540815
(1965)
Sterically controlled iodination of arenes via iridium-catalyzed C-H borylation

Doi:10.1021/ol303164h
(2013)
Mechanochemical aza-vinylogous povarov reactions for the synthesis of highly functionalized 1,2,3,4-tetrahydroquinolines and 1,2,3,4-tetrahydro-1,5-naphthyridines

Doi:10.3390/molecules26051330
(2021)
Oxime esters as acylating agents in the aminolysis reaction. A simple and chemoselective method for the preparation of amides from amino alcohols

Doi:10.1055/s-1991-26553
(1991)

Article Doi