A synthetic approach to aromatic aminoglycoside as a neamine mimic

Article abstract of DOI:10.3987/COM-11-S(P)69

This paper describes the synthetic approach to an aromatic a-glycoside as a mimic of neamine, which is a common core structure of some aminoglycoside antibiotics. We achieved the synthesis of the protected precursor of the neamine mimic, 4-(2,6-diamino-2,