Design, synthesis, and biological evaluations of aplyronine A-mycalolide B hybrid compound

DOI: 10.1021/ol300182r

Source and publish data:

Organic Letters p. 1290 - 1293 (2012)

Update date:2022-07-30

Topics:

Authors:

Kobayashi, Kenichi

Fujii, Yusuke

Hirayama, Yuichiro

Kobayashi, Shinichi

Hayakawa, Ichiro

Kigoshi, Hideo

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Article abstract of DOI:10.1021/ol300182r

A hybrid compound consisting of aplyronine A and mycalolide B was synthesized, and its biological activities were evaluated. The hybrid compound was found to have somewhat more potent actin-depolymerizing activity than aplyronine A. In contrast, the hybri

Full text of DOI:10.1021/ol300182r

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