Synthesis and antimicrobial properties of 3-(β-hydroxyethyl)-1,3- oxazolidins

Article abstract of DOI:10.1134/S1070427212010168

The possibility of synthesis of 3-(β-hydroxyethyl)-1,3-oxazolidin and its substituted derivatives at position 2 by the condensation-heterocyclization of diethanolamine with certain aldehydes and ketones was examined. The structure of the compounds was identifi ed by NMR spectroscopy. We investigated antimicrobial properties of the synthesized compounds against microorganisms that affect the lube oil M-11 and found a dependence of the antimicrobial properties on the nature of the substituent at position 2 of oxazolidin heterocycle.