Synthesis and cytotoxic activity on islets of Langerhans of benzamide thiosemicarbazone derivatives

DOI: 10.1016/0223-5234(91)90059-V

Source and publish data:

European Journal of Medicinal Chemistry p. 273 - 278 (1991)

Update date:2022-08-05

Topics:

Authors:

Campana Campana

Laborie Laborie

Barbier Barbier

Assan Assan

Milcent Milcent

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Article abstract of DOI:10.1016/0223-5234(91)90059-V

Eleven 1-(4-substituted α-arylaminobenzylidene)thiosemicarbazides 1 and the related semicarbazones 2 were synthesized and tested in vitro for their inhibitory effects on the islets of Langerhans. Only the thiosemicarbazones 1 suppressed the insuline and g

Full text of DOI:10.1016/0223-5234(91)90059-V

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