Synthesis of 1-benzyl-3-[4-(aryl-1-piperazinyl) carbonyl]-1h-indoles. novel ligands with potential D4 dopaminergic activity

DOI: 10.4067/S0717-97072011000400009

Source and publish data:

Journal of the Chilean Chemical Society p. 866 - 869 (2011)

Update date:2022-07-29

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Authors:

Pessoa-Mahana, Hernan

Ignacio Cuevas

David Pessoa-Mahana

Araya-Maturana, Ramiro

Fajardo, Iriux Almodovar

Barria, Claudio Saitz

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Article abstract of DOI:10.4067/S0717-97072011000400009

The synthesis of a series of functionalized 1-Benzyl-3-[4-Aryl-1- piperazingl]carbonyl-1H-Indoles 6(a-f), as a potential new class of bioactive ligands at D₄ receptors is reported. The synthetic strategy took place through a five steps sequence

Full text of DOI:10.4067/S0717-97072011000400009

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Product name:1-benzyl-3-{[4-(4-fluorophenyl)-1-piperazinyl]carbonyl}-1H-indole

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