STEREOSELECTIVE ONE-POT SYNTHESES OF TRANS-3-AMINO-β-LACTAMS FROM ZINC ENOLATES OF N-PROTECTED α-AMINOACID ESTERS AND IMINES

DOI: 10.1016/S0040-4039(00)87909-5

Source and publish data:

Tetrahedron Letters p. 2467 - 2470 (1988)

Update date:2022-09-26

Topics:

Authors:

Steen, Fred H. van der

Jastrzebski, Johann T.B.H.

Koten, Gerard van

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Article abstract of DOI:10.1016/S0040-4039(00)87909-5

A new one-pot synthesis of 3-amino-β-lactams that is based on the condensation of simple imines with zinc enolates of disilyl protected glycine esters is reported.Isolated yields are high and a trans-selectivity is observed.

Full text of DOI:10.1016/S0040-4039(00)87909-5

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