Intramolecular cycloaddition reactions of dienyl nitroso compounds: Application to the synthesis of mitomycin K

Article abstract of DOI:10.1021/ja00079a010

The total synthesis of mitomycin K has been achieved. The key reaction produced pyrrolo[1,2-a]indole 25 from dienyl nitrobenzenemethanol 23 by a process involving two internal photochemical redox transformations and a [4 + 2] cycloaddition.