An acid labile arginine derivative for peptide synthesis: N(G)-2,2,5,7,8-pentamethylchroman-6-sulphonyl-L-arginine

DOI: 10.1016/S0040-4020(01)86564-9

Source and publish data:

Tetrahedron p. 6353 - 6370 (1991)

Update date:2022-07-29

Topics:

Authors:

Ramage Ramage

Green Green

Blake Blake

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Article abstract of DOI:10.1016/S0040-4020(01)86564-9

A trifluoroacetic acid (TFA) labile protecting group for the guanidine side chain function of arginine has been developed. N(G)-(2,2,5,7,8-Pentamethylchroman-6-sulphonyl-L-arginine is cleaved rapidly in TFA or 50% TFA in dichloromethane at room temperatur

Full text of DOI:10.1016/S0040-4020(01)86564-9

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Product name:leucinyl-N^G-(2,2,5,7,8-pentamethylchroman-6-sulphonyl)-arginylglycylglycine methyl ester tosylate

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