New C3-synthons for the synthesis of natural products: (R)-glycidaldehyde diethyl dithioacetal and (R)-glycidaldehyde dimethyl acetal

Article abstract of DOI:10.1055/s-1991-26558

The glycidaldehyde acetals (R)-1,1-bis(ethylthio)-2,3-epoxypropane (5) and (R)-2,3-epoxy-1,1-dimethoxypropane (9) were obtained from (R)-2,3-O-isopropylideneglyceraldehyde [(4R)-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde] based on D-mannitol. The applica