Tetrahedron Letters p. 4095 - 4098 (1991)
Update date:2022-08-03
Topics:
Boeckman Jr., Robert K.
Estep, Kimberly G.
Nelson, Scott G.
Walters, Michael A.
A short stereo selective sequence is described for the preparation of the racemic form of the highly functionalized cyclohexene derivative 2 which comprises the upper segment of tetronolide (1), the aglycone of the antitumor tetrocarcins. A key element of this route is rapid assembly and intramolecular cycloaddition of the trienyl enol pyruvate 4, which achieves complete control over regiochemistry and good stereochemical control.
View MoreContact:+86-21-6856-1349 523-87676172
Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
TAIXING BEST NEW MATERIALS CO., LTD
Contact:0523-87998158;
Address:No.18 Zhonggang Road,Taixing City ,Jiangsu , China
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd
Contact:+86-0517-87036900
Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Chengdu Pukang Biotechnology Co., Ltd
website:http://www.pu-kang.com
Contact:86-028-63976226
Address:No. 868 Xiwang Road,Xinjin county,Chengdu city, China
Doi:10.1248/cpb.59.1494
(2011)Doi:10.1021/jo01037a068
(1963)Doi:10.1016/j.ejmech.2020.112942
(2021)Doi:10.1002/asia.201100926
(2012)Doi:10.1021/ja00024a030
(1991)Doi:10.1039/c0cc00739k
(2010)