Efficient synthesis of 3-substituted lactams using Meerwein Eschenmoser Claisen [3,3] sigmatropic rearrangements

DOI: 10.1016/S0040-4039(00)79904-7

Source and publish data:

Tetrahedron Letters p. 4199 - 4202 (1991)

Update date:2022-09-26

Topics:

Authors:

Coates Coates

Montgomery

Stevenson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)79904-7

3-Allyl substituted five, six and seven membered ring lactams are readily available in good yields and reasonable selectivity by a formal Meerwein Eschenmoser Claisen [3,3] rearrangement, using the readily available N,N-dialkylalkoxymethylene iminium salts and lithium alkoxides derived from allyl alcohols.

Full text of DOI:10.1016/S0040-4039(00)79904-7

Products guided by the article

Product name:1-Methyl-3-(1-phenyl-allyl)-azepan-2-one

Cas No:136866-75-6

R&D Labs maybe for 136866-75-6

Beijing Green Guardee Technology CO,.LTD

Contact:+86-10-69706062

Address:F2 BLdj,5 No.37 Chaoqian Road
Refine Chemicals Science & Technology Technology Developing Co., Ltd.

Contact:+86-22-87899130

Address:No.12,west keyan road,Tianjin City
Qida Chemical Co., Ltd.(expird)

Contact:+86-25-8776 0031

Address:3-2001 Jiaye Int'l Town, 158 Lushan Road,Nanjing, 210019, China
Shochem(Shanghai) Co., Ltd

website:http://www.shochem.com

Contact:021-50800795

Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Huangshan Honghui Pharm Technology Co., Ltd.(expird)

website:http://www.honghuichem.com

Contact:18855958372

Address:Qingshan Wan No.1,Nanyuan Kou,SheXian Huangshan City,Anhui Province

Relevant to this article

Iodine-catalyzed three-component one-pot synthesis of naphthopyranopyrimidines under solvent-free conditions

Doi:10.1016/j.tetlet.2012.01.096
(2012)
Discovery of epigenetic regulator i-bet762: Lead optimization to afford a clinical candidate inhibitor of the bet bromodomains

Doi:10.1021/jm401088k
(2013)
Efficient synthesis of 2-arylquinazolin-4-amines via a copper-catalyzed diazidation and ring expansion cascade of 2-arylindoles

Doi:10.1039/C8CC07721E
(2018)
Semipreparative HPLC enantioseparation, chiroptical properties, and absolute configuration of two novel cyclooxygenase-2 inhibitors

Doi:10.1002/chir.20705
(2010)
Catalytic asymmetric alkylation of α-cyanocarboxylates and acetoacetates using a phase-transfer catalyst

Doi:10.1016/j.tetasy.2009.10.018
(2009)
One-step conversion of acetophenones to α-haloacetophenone dimethyl acetals using DCDMH/DBDMH and molecular sieve in methanol

Doi:10.1080/00397911.2010.540696
(2012)

Article Doi