Tetrahedron Asymmetry p. 1049 - 1054 (1992)
Update date:2022-07-29
Topics:
Wirz, Beat
Walther, Willy
t-Butyl (R)-3-(hydroxymethyl)-1-piperidinecarboxylate was prepared with lipase P in up to 98 percent ee by means of enantioselective esterification of the racemic alcohol as well as by enantioselective hydrolysis of the corresponding butyryl ester and subsequent chemical hydrolysis of the retained (R)-ester.A work-up procedure feasible on the kg-scale is described.
View MoreContact:+8618766299236
Address:ROOM808, BUILDING2,NO.230 SHEN ZHEN ROAD, LAOSHAN DISTRICT
website:http://www.antimex.com
Contact:0086-21-50563169
Address:Room1027,No.Jinyu Road,Pudong
Jiangsu Hualun Chemical Industry Co., Ltd
website:http://www.hualunchem.com
Contact:+86-0514-86464168 86507985
Address:39# Middle Renmin Road, Dinghuo Town
Zhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
AstaTech ( Chengdu) BioPharmaceutical Corp.
website:http://www.astabiochem.cn/
Contact:+86-15198215156-15198215156
Address:SICHUAN CHENGDU
Doi:10.1016/S0040-4039(00)94780-4
(1985)Doi:10.1021/jm2001597
(2011)Doi:10.1007/s00706-011-0468-8
(2011)Doi:10.1016/j.cclet.2016.09.006
(2017)Doi:10.1021/ol201717d
(2011)Doi:10.1002/jlcr.3557
(2017)
