Copper-catalyzed synthesis of 1,2,4-trisubstituted pyrroles via cascade reactions of aryloxy-enynes with amines

Article abstract of DOI:10.1039/c3ra44595j

A highly efficient copper-catalyzed cascade reaction of aryloxy-enynes with amines under mild reaction conditions has been developed. This methodology offers rapid access to 1,2,4-trisubstituted pyrroles in good to excellent yields in a regioselective manner.