Synthesis of Substituted 2-Aminoquinoline-1-oxides by Reductive Cyclization of Substituted 3-(2-Nitrophenyl)acrylonitriles

Article abstract of DOI:10.1002/prac.19923340114

An approach to the class of 2-aminoquinoline-1-oxides is given based on reductive cyclization of appropriate substituted 3-(2-nitrophenyl)acrylonitriles.Thus, 2-nitrobenzylidene compounds 1a-d have been reductively cyclized by H2/PtO2 or H2/Pd-C under nor