Design, synthesis and antifibrotic activities of carbohydrate-modified 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones

DOI: 10.3390/molecules17010884

Source and publish data:

Molecules p. 884 - 896 (2012)

Update date:2022-08-05

Topics:

Authors:

Lou, Qinghua

Meng, Xiangbao

Lao, Zhiqi

Xuan, Lingling

Bai, Jinye

Hou, Qi Hou, Qi

Hu, Gaoyun

Luo, Renna

Tao, Lijian

Li, Zhongjun

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3390/molecules17010884

Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl- 2(1H) pyridones modified with

Full text of DOI:10.3390/molecules17010884

Products guided by the article

Product name:1,2;3,4-di-O-isopropylidene-6-deoxy-6-(3-(5-trifluoromethyl-2(1H)-pyridone-1-yl-methyl)-anilino)-α-D-galactopyranose

Cas No:1372204-30-2

R&D Labs maybe for 1372204-30-2

Hopechem Co., Ltd.

Contact:+86-20-38011066

Address:3510, Diwang Commercial Center, 5002 Shennan Rd, Shenzhen, P.R.China
CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Angel Yeast Co., Ltd.

Contact:+86-717-6370352

Address:168 Chengdong Avenue, Yichang, Hubei 443003, P. R.China
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.

Contact:+86-512-6585 6968

Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Sinochem Jiangsu Co.,Ltd.

Contact:86-25-51817806

Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china

Relevant to this article

Unusual Formation of Cyclopenta[ b]indoles from 3-Indolylmethanols and Alkynes

Doi:10.1021/acs.joc.8b03027
(2019)
Organocatalytic synthesis of (Arylselanyl)phenyl-1H-1,2,3-triazole-4- carboxamides by cycloaddition between azidophenyl arylselenides and β-oxo-amides

Doi:10.1002/ejoc.201301547
(2014)
Evaluation of Cytochrome P450 Selectivity for Hydralazine as an Aldehyde Oxidase Inhibitor for Reaction Phenotyping

Doi:10.1016/j.xphs.2018.11.007
(2019)
Catalytic asymmetric synthesis of [2,3]-fused indoline heterocycles through inverse-electron-demand aza-Diels-Alder reaction of indoles with azoalkenes

Doi:10.1002/anie.201400109
(2014)
Synthesis and antitumor activity of a new class of pyrazolo[4,3- e]pyrrolo[1,2-a][1,4]diazepinone analogues of pyrrolo[1,4][2,1- c]benzodiazepines

Doi:10.1021/jm00051a009
(1994)
Synthesis of cyclo-L-rhamnopentaose

Doi:10.1248/cpb.42.1365
(1994)

Article Doi