Application of [3+2]-cycloaddition in the synthesis of valdecoxib

DOI: 10.1080/00397911.2010.528572

Source and publish data:

Synthetic Communications p. 639 - 649 (2012)

Update date:2022-08-03

Topics:

Authors:

Reddy, Anumula Raghupathi

Goverdhan, Gilla

Sampath, Aalla

Mukkanti, Khagga

Reddy, Padi Pratap

Bandichhor, Rakeshwar

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1080/00397911.2010.528572

A large scale synthesis of valdecoxib 1 is described. Our work features potential application of [3+2]-dipolar cycloaddition involving enamine and in situ-generated nitrile oxide derivatives. Dr. Reddy's Laboratories Ltd.

Full text of DOI:10.1080/00397911.2010.528572

Products guided by the article

Product name:Valdecoxib IMpurity B

Cas No:1373038-60-8

R&D Labs maybe for 1373038-60-8

JiYi Chemical (Beijing) Co., Ltd.

Contact:+86-10-89385733

Address:Shilou Town of Fangshan District， Beijing
Suzhou Kangrun Pharmaceutical, Inc

Contact:86-512-63912376，63913329

Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Xi'an North Information Industry Co., Ltd. Weilv Chemical Department

Contact:+86-29-88156413

Address:Jixiang Road 99 Xi'an Shaanxi Province
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.

Contact:+86-0150-58101658

Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China

Relevant to this article

Combination of amino acid/dipeptide with ligustrazine-betulinic acid as antitumor agents

Doi:10.1016/j.ejmech.2017.02.036
(2017)
A cascade reaction of pyrrole-2-carbaldehyde substituted Morita-Baylis-Hillman adducts in the presence of tetrabutylammonium hydroxide or acetate to construct aza-heterocycles

Doi:10.1039/c2cc31358h
(2012)
Ni(II)-POCOP pincer compound [NiCl{C₁₀H₅-2,10- (OPPh₂)₂}] an efficient and robust nickel catalyst for the Suzuki-Miyaura coupling reactions

Doi:10.1016/j.ica.2011.12.052
(2012)
Smooth Metal-Free Photoinduced Preparation of Valuable 8-Arylxanthines

Doi:10.1002/ejoc.201900638
(2020)
Regioselective synthesis of fused azo-linked pyrazolo[4,3-e]pyridines using nano-Fe₃O₄

Doi:10.1002/cjoc.201100181
(2012)
Development of a novel series of styrylquinoline compounds as high- affinity leukotriene D₄ receptor antagonists: Synthetic and structure- activity studies leading to the discovery of (±)-3-[[[3-[2-(7-chloro-2- quinolinyl)-(E)-ethenyl]phenyl][[3-(dimethylamino)-3- oxopropyl]thio]methyl]thio]propionic acid

Doi:10.1021/jm00099a011
(1992)

Article Doi