Microwave-assisted synthesis of 1,3-disubstituted β-carbolines from β-(alkylideneamino)nitriles and gramine

DOI: 10.1055/s-0031-1289675

Source and publish data:

Synthesis p. 747 - 754 (2012)

Update date:2022-08-05

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Authors:

Letessier, Julien

Detert, Heiner

Goetz, Katharina

Opatz, Till

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Article abstract of DOI:10.1055/s-0031-1289675

Reaction of deprotonated α-(alkylidenamino)nitriles with gramine in the presence of tributylphosphine furnishes -substituted imines of tryptophane nitrile. Their subsequent intramolecular cyclization followed by dehydrocyanation and oxidation affords 1,3-

Full text of DOI:10.1055/s-0031-1289675

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