Journal of Medicinal Chemistry p. 233 - 241 (1992)
Update date:2022-08-05
Topics:
Johnson, Graham
Drummond, James T.
Boxer, Peter A.
Bruns, Robert F.
3-Carboxy-3,4-dehydropyrrolidine was found to bind with affinity equal to that of glycine in a <3H>strychnine binding assay.Simple substitution of the 1-, 2-, 4-, or 5-position resulted in marked loss of affinity.A decaline in affinity was also found upon
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