Studies on immunostimulating derivatives: Synthesis of some pyrrolo[1,2-c]pyrimidines

DOI: 10.1248/cpb.39.2126

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2126 - 2128 (1991)

Update date:2022-07-29

Topics:

Authors:

Bahaji Bahaji

Tronche Tronche

Couquelet

Harraga Harraga

Panouse-Perrin

Rubat Rubat

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Article abstract of DOI:10.1248/cpb.39.2126

In a search for potential immunomodulating agents novel pyrrolo[1,2-c]pyrimidines were synthesized and their structures elucidated by spectroscopic means. Unfortunately, most of them were cytotoxic and devoid of effects on T lymphocyte lymphoblastic transformation. Furthermore, they were inactive in the locomotor activity test in mice.

Full text of DOI:10.1248/cpb.39.2126

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