
Chemical and Pharmaceutical Bulletin p. 2126 - 2128 (1991)
Update date:2022-07-29
Topics:
Bahaji
Tronche
Couquelet
Harraga
Panouse-Perrin
Rubat
In a search for potential immunomodulating agents novel pyrrolo[1,2-c]pyrimidines were synthesized and their structures elucidated by spectroscopic means. Unfortunately, most of them were cytotoxic and devoid of effects on T lymphocyte lymphoblastic transformation. Furthermore, they were inactive in the locomotor activity test in mice.
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(1994)