A Synthesis of (+)-7-Epiaustraline and (-)-7-Epialexine

DOI: 10.1016/0040-4039(91)80071-D

Source and publish data:

Tetrahedron Letters p. 5513 - 5516 (1991)

Update date:2022-08-05

Topics:

Authors:

Pearson, William H.

Hines, Jennifer V.

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Article abstract of DOI:10.1016/0040-4039(91)80071-D

Reductive cyclization of the azido epoxides 19α and 19β followed by deprotection afforded the HIV inhibitor (+)-7-epiaustraline 7 and (-)-7-epialexine 9.The formation of 7 proceeded with an unusual inversion of configuration at C-7.Key Words: (+)-7-Epiaus

Full text of DOI:10.1016/0040-4039(91)80071-D

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