Total synthesis of herbimycin A

DOI: 10.1016/S0040-4039(00)79452-4

Source and publish data:

Tetrahedron Letters p. 6015 - 6018 (1991)

Update date:2022-08-05

Topics:

Authors:

Nakata Nakata

Osumi Osumi

Ueno Ueno

Kimura Kimura

Tamai Tamai

Tatsuta Tatsuta

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Article abstract of DOI:10.1016/S0040-4039(00)79452-4

The first total synthesis of herbimycin A (1), the benzoquinoid ansamycin antibiotic, has been accomplished by coupling two segments of the aliphatic ansa-chain 2 and the aromatic chromophore 3, elucidating the absolute stereochemistry.

Full text of DOI:10.1016/S0040-4039(00)79452-4

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