Synthesis of Biological Markers in Fossil Fuels. 2. Synthesis and 13C NMR Studies of Substituted Indans and Tetralins

Article abstract of DOI:10.1021/jo00196a024

Unambiguous syntheses of all possible methyl, ethyl, n-propyl, and n-butyl derivatives of indan and tetralin were developed using the Kumada coupling procedure involving the reaction of aryl or vinyl halides with Grignard reagents in the presence of <1,3-bis(diphenylphosphino)propyl>nickel(II) chloride.An analysis of the 13C NMR spectra of these compounds was also completed.