
Journal of Medicinal Chemistry p. 676 - 683 (1992)
Update date:2022-07-30
Topics:
Carceller
Merlos
Giral
Bartroli
Garcia-Rafanell
Forn
A series of 4-substituted 2-alkoxytetrahydrofuran derivatives featuring an acetal group were prepared and evaluated for PAF antagonist activity in the PAF-induced in vitro platelet-aggregation and in vivo hypotension tests. Compound 2-[[N-acetyl-N-[[[2-(o
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