4-Substituted 2-alkoxytetrahydrofurans as potent and long-lasting PAF antagonists

DOI: 10.1021/jm00082a007

Source and publish data:

Journal of Medicinal Chemistry p. 676 - 683 (1992)

Update date:2022-07-30

Topics:

Authors:

Carceller

Merlos Merlos

Giral Giral

Bartroli

Garcia-Rafanell

Forn Forn

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00082a007

A series of 4-substituted 2-alkoxytetrahydrofuran derivatives featuring an acetal group were prepared and evaluated for PAF antagonist activity in the PAF-induced in vitro platelet-aggregation and in vivo hypotension tests. Compound 2-[[N-acetyl-N-[[[2-(o

Full text of DOI:10.1021/jm00082a007

Products guided by the article

Product name:Carbonic acid, phenyl (tetrahydro-5-methoxy-3-furanyl)methyl ester, cis-

Cas No:138060-24-9

R&D Labs maybe for 138060-24-9

Shanghai doly chemical Co.,Ltd

Contact:+86-21-34716221

Address:No.328,WuHe Roard,MinHang,ShangHai China
chengdu firsterchem Pharmaceutical Co., Ltd.

Contact:028-66825849

Address:chengdu
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
He Bei Shun Er Chemical Co., LTD.

Contact:86-0311-86996932/86860168

Address:No 18,North street
Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province

Relevant to this article

One-pot synthesis of 1-aryl-1 H,3 H-thiazolo[3,4-a[benzimidazoles using magnetite-linked sulfonic acid as catalyst

Doi:10.1080/10426507.2014.906421
(2014)
Silacupration of Oxabicyclic Compounds. An Interrupted Ring Opening Reaction

Doi:10.1021/jo00028a003
(1992)
Selective Isomerization of Glycidates and Their Analogues with Triphenylsilyl Perchlorate or Electrogenerated Acid

Doi:10.1246/cl.1991.2009
(1991)
Identification of hydroxybenzoic acids as selective lactate receptor (GPR81) agonists with antilipolytic effects

Doi:10.1021/ml3000676
(2012)
Synthesis of spirocyclic γ-lactones by cascade Beckwith-Dowd ring expansion/cyclization

Doi:10.1021/ol301386k
(2012)
Synthesis, crystal structure, and fungicidal activity of a novel 1,2,3-thiadiazole compound

Doi:10.1080/10426507.2012.664219
(2012)

Article Doi