Diastereoselectivity in the Hydroxyl-Directed Cyclopropanation of Vinylorganometallic Compounds

DOI: 10.1021/jo00029a004

Source and publish data:

Journal of Organic Chemistry p. 798 - 800 (1992)

Update date:2022-07-30

Topics:

Authors:

Lautens, Mark

Delanghe, Patrick H. M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00029a004

Olefins bearing silicon and/or tin substituents undergo highly diastereoselective cyclopropanation in the presence of Sm/CH2I2.The stereochemistry of the tin moiety has a dramatic effect on the rate of a subsequent transmetalation with MeLi.

Full text of DOI:10.1021/jo00029a004

Products guided by the article

Product name:[(R)-((1R,2R)-2-Butyl-cyclopropyl)-methoxy-methyl]-cyclohexane

Cas No:138154-10-6

R&D Labs maybe for 138154-10-6

Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)

Contact:+86-523-86818997

Address:Taizhou,Jiangsu Province,CHINA
Wuhan Konberd Biotech Co., Ltd.

Contact:+86-27-87205925

Address:NO.666, Gaoxin Road, Eastlake High-tech zone
Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Shandong Xinhua Pharmaceutical Co.,Ltd

website:http://www.xhzy.com

Contact:+86-533-2196801

Address:1 lutai road,zhangdian dis,Zibo City

Relevant to this article

Construction of chiral 2-substituted octahydroindoles from cyclic ketones and nitroolefins bearing only one α-substituent

Doi:10.1002/adsc.201400851
(2015)
Highly regioselective transformation of out/out-equatorial bis(formylmethano)[60]fullerenes: Construction of dissymmetric [60]fullerene-centered triads

Doi:10.1021/jo060110+
(2006)
A Divergent Entry into Prostaglandin Synthesis through 1,4-Addition of Methoxy(phenylthio)(trimethylsilyl)methyllithium to 4-Siloxy-2-cyclopentenone

Doi:10.1016/S0040-4039(00)92528-0
(1992)
Oxidative decarboxylation of α-hydroxy acids by a functional model of the nonheme iron oxygenase, CloR

Doi:10.1039/b925389k
(2010)
Copper- and phosphine-ligand-free palladium-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides

Doi:10.1002/chem.201202824
(2012)
Total Synthesis of (-)-Detoxin D₁

Doi:10.1016/S0040-4039(00)92511-5
(1992)

Article Doi